نشریه بین المللی نوآوری در مدیریت ، اقتصاد و توسعه 4 2 Enhancing SMEs Performance: The Impact of Supply Chain Strategy, Marketing Orientation, and Sustainable Entrepreneurial Orientation Enhancing SMEs Performance: The Impact of Supply Chain Strategy, Marketing Orientation, and Sustainable Entrepreneurial Orientation 113 133 10.22051/jera.2021.31891.2698 FA Sepideh Assistant Professor, Faculty of Finance & Accounting, Iranian eUniversity, Tehran, Iran Sara Master's Student, Electronic Branch, Islamic Azad University, Tehran, Iran Roozbeh Lecturer, Faculty of Finance & Accounting, Iranian eUniversity, Tehran, Iran 2024 08 26 In contemporary times, sustainable entrepreneurial orientation and market orientation are essential determinants for organizations to thrive in competitive environments. This research seeks to examine the impacts of sustainable entrepreneurial orientation and market orientation on the performance of small and medium-sized enterprises (SMEs) within the pharmaceutical industries, utilizing a supply chain strategy framework. To achieve this objective, four hypotheses were formulated. A researcher-designed questionnaire comprising 34 items was employed to test these hypotheses, and it was distributed among 110 managers in the pharmaceutical industry. The quantitative data were analyzed using SPSS 27.0 and AMOS 26.0. The findings revealed that market orientation significantly enhances the organizational performance of pharmaceutical companies. Furthermore, sustainable entrepreneurial orientation is pivotal in improving organizational performance outcomes. Sustainable entrepreneurial orientation significantly contributes to augmenting supply chain collaboration, and subsequently, organizational performance is instrumental in further enhancing supply chain (SC) collaboration. In contemporary times, sustainable entrepreneurial orientation and market orientation are essential determinants for organizations to thrive in competitive environments. This research seeks to examine the impacts of sustainable entrepreneurial orientation and market orientation on the performance of small and medium-sized enterprises (SMEs) within the pharmaceutical industries, utilizing a supply chain strategy framework. To achieve this objective, four hypotheses were formulated. A researcher-designed questionnaire comprising 34 items was employed to test these hypotheses, and it was distributed among 110 managers in the pharmaceutical industry. The quantitative data were analyzed using SPSS 27.0 and AMOS 26.0. The findings revealed that market orientation significantly enhances the organizational performance of pharmaceutical companies. Furthermore, sustainable entrepreneurial orientation is pivotal in improving organizational performance outcomes. Sustainable entrepreneurial orientation significantly contributes to augmenting supply chain collaboration, and subsequently, organizational performance is instrumental in further enhancing supply chain (SC) collaboration. /downloadfilepdf/661781